# Nature Portfolio Playbook > Use when choosing among Nature, Nature Methods, or Nature Biotechnology, or when preparing a Nature Portfolio life-science manuscript for venue fit, article-type framing, and policy-aware pre-submission checks. - **Type:** Skill - **Install:** `agentstack add skill-boom5426-nature-paper-skills-nature-portfolio-playbook` - **Verified:** Yes — security-reviewed for prompt injection and unsafe behavior - **Seller:** [Boom5426](https://agentstack.voostack.com/s/boom5426) - **Installs:** 0 - **Category:** [Agent Skills](https://agentstack.voostack.com/c/agent-skills) - **Latest version:** 0.1.0 - **License:** MIT - **Upstream author:** [Boom5426](https://github.com/Boom5426) - **Source:** https://github.com/Boom5426/Nature-Paper-Skills/tree/main/skills/venue/nature-portfolio-playbook ## Install ```sh agentstack add skill-boom5426-nature-paper-skills-nature-portfolio-playbook ``` Requires the [AgentStack CLI](https://agentstack.voostack.com/docs/cli). Works with Claude Code, Cursor, and any MCP-compatible agent. ## About # Nature Portfolio Playbook ## Overview Use this skill when the venue decision itself is still live, or when a manuscript already targets `Nature`, `Nature Methods`, or `Nature Biotechnology` and needs venue-specific framing before a heavy revision pass. This skill is about fit and policy. It does not replace `scientific-writing`, `manuscript-optimizer`, or `submission-audit`. ## When To Use Use this skill when: - the user asks whether a story fits `Nature`, `Nature Methods`, or `Nature Biotechnology` - the paper has a `Nature`-style tone but the actual venue is undecided - the contribution could be framed as an `Article`, `Resource`, `Analysis`, or short-format methods report - a manuscript is close to submission and needs a Nature Portfolio-specific preflight Do not use this skill when: - the task is generic sentence-level editing - the venue is a conference or a non-Nature journal - the manuscript structure itself is still unstable and needs `manuscript-optimizer` first ## Venue Routing ### Flagship `Nature` Default to `Nature` only when the paper makes a broad conceptual advance that matters outside the immediate specialty and can be explained to non-specialists without heavy field-specific scaffolding. Use these framing defaults: - prioritize broad readership over specialist density - keep title and abstract low-jargon - preserve the non-specialist-friendly summary paragraph expectation - if fit is uncertain, explicitly test whether the broad-readership case is real before optimizing prose too far ### `Nature Methods` Prefer `Nature Methods` when the central contribution is a method, assay, platform, computational approach, or resource whose main claim is enabling power. Before calling a story `Nature Methods`-fit, check that the manuscript can support all of these: - a clear technical advance over available approaches - validation and benchmarking against credible baselines or alternatives - enough detail or protocol access for reproducibility - demonstrated general utility, not just one narrow showcase - a compelling biological or biomedical application that shows why the method matters ### `Nature Biotechnology` Prefer `Nature Biotechnology` when the paper's value is not just technical novelty but biotechnology significance: enabling capability, translational relevance, engineering depth, platform utility, or community-scale resource value. Before calling a story `Nature Biotechnology`-fit, check that the manuscript can make legible: - why the advance matters for biotechnology or medicine, not just for one specialist benchmark - why the story is substantial enough for a full article rather than a narrower methods report - whether the paper is truly an `Article` or would be better framed as a `Resource` ## Article-Type Check Do this early. Do not treat article type as formatting cleanup. - `Article`: full research story with multiple linked claims and a substantial evidence chain - `Resource`: community-useful dataset, platform, atlas, database, or screening asset whose lasting value is broad reuse - `Analysis`: integrative or comparative analytical study when the core contribution is the analytical insight rather than a new experimental method - short-format method/report categories: use only when the story is tighter, more self-contained, and the journal explicitly supports that format If the manuscript keeps oscillating between `method paper` and `resource paper`, resolve that before rewriting the abstract or Results. ## Nature Portfolio Preflight Run this before calling a draft submission-ready: 1. Reporting standards - confirm whether a reporting summary will be required - make sure the manuscript and supplement already contain the information that summary will demand 2. Data and code availability - check that repository names, accession IDs, download links, and access restrictions are ready to disclose - do not wait until after acceptance to figure out the data/code statement 3. Protocol and reproducibility readiness - for methods papers, ensure the usable protocol path is clear: supplement, protocol repository, or public method record 4. Image integrity and raw data - ensure unprocessed source images and raw blot/gel material can be produced if requested - remove any figure-preparation habit that could look like selective enhancement 5. AI and attribution - disclose qualifying use of generative AI tools where the journal requires it - do not treat AI-made images or undisclosed AI-written content as safe by default 6. Related-manuscript and preprint disclosures - disclose preprints, overlapping submissions, related manuscripts, and conference-proceedings history when relevant ## Working Rule Use this decision order: 1. choose audience and venue family 2. choose article type 3. check whether the evidence package matches the venue promise 4. only then optimize framing and prose ## Official Source Pointers Keep these Nature Portfolio pages as the primary references: - `Nature` formatting guide - `Nature` editorial criteria and processes - `Nature Methods` aims, content, and editorial-policies pages - `Nature Biotechnology` aims, content, and editorial-policies pages - Nature Portfolio policies on reporting standards, image integrity, AI, and preprints/conference proceedings ## Source & license This open-source skill is cataloged on AgentStack and links to its original source — we do not rehost the code. - **Author:** [Boom5426](https://github.com/Boom5426) - **Source:** [Boom5426/Nature-Paper-Skills](https://github.com/Boom5426/Nature-Paper-Skills) - **License:** MIT Install and usage instructions live in the source repository linked above. ## Pricing - **Free** — Free ## Security capabilities Automated source analysis of v0.1.0 — what this tool can access: - **Network access:** no - **Filesystem access:** no - **Shell / process execution:** no - **Environment & secrets:** no - **Dynamic code execution:** no *"Yes" means the capability is present in the source — more access means more to trust, not that it is unsafe.* ## Versions - **0.1.0** — security scan: passed — Imported from the upstream source. ## Links - Listing page: https://agentstack.voostack.com/l/skill-boom5426-nature-paper-skills-nature-portfolio-playbook - Seller: https://agentstack.voostack.com/s/boom5426 - Browse the marketplace: https://agentstack.voostack.com/browse --- Listed on AgentStack — the marketplace for AI agent skills and MCP servers. Every listing is security-reviewed. Creators keep 70%.