Fine Mapping
Statistical fine-mapping of GWAS loci using SuSiE, SuSiE-inf, and Approximate Bayes Factors to identify credible
Genome Match
Score genetic compatibility across all male-female pairings in a Genomebook generation
Gwas Catalog Region Fetch
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Claw Semantic Sim
Semantic Similarity Index for disease research literature using PubMedBERT embeddings
Claw Methylation Cycle
Methylation cycle analysis — enzymatic activity profiles, Net Methylation Capacity, BH4 axis estimates, compound heterozygosity detection from SNP genotype data.
Gwas Lookup
Federated variant lookup across 9 genomic databases — GWAS Catalog, Open Targets, PheWeb (UKB, FinnGen, BBJ),
Gwas Prs
Calculate polygenic risk scores from DTC genetic data using the PGS Catalog
Gi Splice
Detect splice donor and acceptor sites in DNA sequences using the Genomic Intelligence G0 BigBird transformer, via the hosted /v1/tasks/splice/predict API. Returns per-position site probabilities
Gi Promoter
Detect promoter regions in DNA sequences using the Genomic Intelligence G0 transformer (GENA-LM BERT Large), via the hosted /v1/tasks/promoter/predict API. Returns per-window promoter probabilities
Eqtl Catalogue Region Fetch
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Drug Repurposing Screen
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Clinical Variant Reporter
Classify germline variants from VCF/BCF files according to the ACMG/AMP 2015 28-criteria evidence framework and
Archaic Introgression
Detect Neanderthal and Denisovan introgression segments from modern human genomes
Bigquery Public
Run read-only SQL against BigQuery public datasets with local result capture, cost safeguards, and reproducibility
Bio Orchestrator
Meta-agent that routes bioinformatics requests to specialised sub-skills. Handles file type detection, analysis
Galaxy Bridge
Galaxy tool discovery, intelligent recommendation, and execution — 8,000+ bioinformatics tools from usegalaxy.org
Flow Bio
Flow.bio API bridge — authenticate, browse pipelines/samples/projects, search, upload data, launch pipeline executions,
Equity Scorer
Compute HEIM diversity and equity metrics from VCF or ancestry data. Generates heterozygosity, FST, PCA plots,
Busco Assessor
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Clinical Trial Finder
Find clinical trials for a gene, variant, or condition from ClinicalTrials.gov + EUCTR, with FHIR R4 output
Claw Ancestry Pca
Ancestry decomposition PCA against the Simons Genome Diversity Project
Gi Enhancer
Predict enhancer activity in DNA sequences using the Genomic Intelligence G0 DeepSTARR model, via the hosted /v1/tasks/enhancer/predict API. Returns per-window activity scores.
Claw Metagenomics
Shotgun metagenomics profiling — taxonomy, resistome, and functional pathways
Illumina Bridge
Import DRAGEN-exported Illumina result bundles into ClawBio for local tertiary analysis and downstream routing.
Drug Photo
Medication photo to personalised PGx dosage card via Claude vision — snap a pill, get genotype-informed guidance
Diff Visualizer
Rich downstream visualisation and reporting for bulk RNA-seq differential expression and scRNA marker/contrast
Affinity Proteomics
Unified analysis pipeline for affinity-based proteomics platforms — Olink (PEA, NPX) and SomaLogic SomaScan (SOMAmer,
De Summary
Summarise pre-computed differential expression results with ranked gene lists, biological themes, and publication-ready
Labstep
Query and display Labstep electronic lab notebook data — experiments, protocols, resources, and inventory — via
Bioqc Mcp
Automated sequencing quality control and advanced visualization wrapping FastQC, MultiQC, and custom chart generation. Exposes an MCP stdio server for live AI integration alongside a ClawBio CLI runner.
Article Data Fetcher
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Bioconductor Bridge
Bioconductor package discovery, workflow recommendation, setup inspection, and starter code generation grounded
Genome Compare
Compare your genome to George Church (PGP-1) and estimate ancestry composition via IBS and EM admixture
Data Extractor
Extract numerical data from scientific figure images using Claude vision + OpenCV calibration. Supports 26+ plot
Gi Annotation
Predict gene and transcript structure (intervals, exons, strand) from a DNA sequence using the Genomic Intelligence DNA Annotation model, via the hosted /v1/tasks/annotation/predict API. Async-only
Gi Expression
Predict tissue / cell-type expression (log TPM + TPM) from a 9,198 bp TSS-centered DNA sequence using the Genomic Intelligence G0 Expression model, via the hosted /v1/tasks/expression/predict
Dnasp
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Gi Chromatin
Predict chromatin state — histone marks, DNase, TF binding — across 919 tracks (DeepSEA-style) for DNA sequences, via the hosted Genomic Intelligence /v1/tasks/chromatin/predict API.
Fastreer
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Gwas Pipeline
End-to-end GWAS automation wrapping PLINK2 for genotype QC and REGENIE for two-step whole-genome regression association
Analyze Fasta
Analyze a single FASTA file (nucleotide or protein), compute sequence-level metrics (GC, ORFs, MW, pI, GRAVY, secondary-structure fractions) with Biopython, and write a Markdown report plus structured JSON for downstream chaining.
Hla Typing
HLA allele typing from WGS/WES VCF data
Cnv Acmg Classifier
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Celltype Specificity Profiler
Given a gene and a single-cell atlas, compute how cell-type-specific its expression is — the tau specificity index, Sarle's expression bimodality coefficient, and the cell types that drive the signal; a pure analytic transform that chains downstream of scrna-embedding.
Cell Detection
Cell segmentation in fluorescence microscopy images. Supports Cellpose/cpsam (Cellpose 4.0) with additional backends
Crispr Screen Triage
Deterministic CRISPR screen hit ranking from local guide-level count tables
Clawpathy Autoresearch
Eval-driven skill tuning. Given a task and an LLM-judge rubric, iteratively rewrites a SKILL.md until a downstream executor agent performs well against the judge. Low-code: all evaluation
Clinpgx
Query the ClinPGx API for pharmacogenomic gene-drug data, clinical annotations, CPIC guidelines, and FDA drug
Skill
A Claude skill from ClawBio/ClawBio.
Bgpt Mcp
Search scientific papers via the BGPT MCP server and retrieve structured experimental data — methods, results,