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SKILL verified Apache-2.0 Self-run

Evo2

skill-xuzhougeng-wisp-science-evo2 · by xuzhougeng

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Install

$ agentstack add skill-xuzhougeng-wisp-science-evo2

✓ scanned · ✓ verified, works with Claude Code, Cursor, and more.

Security review

✓ Passed

No issues found. Passed automated security review. · v0.1.0 How review works →

  • Prompt-injection patterns
  • Secret / credential exfiltration
  • Dangerous shell & filesystem operations
  • Untrusted network calls
  • Known-malicious package signatures

What it can access

  • Network access No
  • Filesystem access No
  • Shell / process execution No
  • Environment & secrets No
  • Dynamic code execution No

From automated source analysis of v0.1.0. “Used” means the capability is present in the source — more access means more to trust, not that it’s unsafe.

View the full security report →

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Reliability & compatibility

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2mo ago

Declared compatibility

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Compatibility is declared by the source manifest. End-to-end runtime verification is coming, see below.

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About

Evo 2 — DNA Language Model

Prerequisites

| Requirement | Minimum | Recommended | | ----------- | ------- | ---------------- | | Python | 3.11 | 3.12 (/


For the full result dict (`output_files`, `remote_workdir`, …), re-enter the
kernel: `c.attach_job(job_id).result()` then `c.close()`. See the
`remote-compute-ssh` / `remote-compute-modal` skill for the orchestration
details.

Inside `score_evo2.py`, point `HF_HOME` at the provider's weight-cache mount
(path is in `compute_details`) and set `HF_HUB_OFFLINE=1` so the loader
doesn't try to write `refs/` into a read-only mount. Weight footprint:
~15 GB (7B), ~80 GB (40B).

## Typical performance

| Task                        | 7B on H100 | Notes                       |
| --------------------------- | ---------- | --------------------------- |
| Model load (cached)         | ~5-7 min   | First call hydrates weights |
| `score_sequences`, 200×200bp| ~10-20 s   | After load                  |
| `generate`, 1×512 nt        | ~15 s      |                             |

## Troubleshooting

| Symptom                              | Cause                          | Fix                                        |
| ------------------------------------ | ------------------------------ | ------------------------------------------ |
| `Transformer Engine not installed`   | No FP8 — falls back to bf16    | Informational only on non-H100; ignore     |
| OOM on load                          | 40B on <80 GB GPU              | Use `evo2_7b` or shard with `device_map`   |
| HF tries to write `refs/main`        | `HF_HOME` points at RO mount   | Set `HF_HUB_OFFLINE=1`                     |
| `dtype mismatch` in `score_sequences`| Passing tensors not strings    | Pass `list[str]`; the API tokenises for you |

---

**Next**: pair with `borzoi` to predict track-level effects of the same
variants.

## Source & license

This open-source skill is cataloged on AgentStack and links to its original source — we do not rehost the code.

- **Author:** [xuzhougeng](https://github.com/xuzhougeng)
- **Source:** [xuzhougeng/wisp-science](https://github.com/xuzhougeng/wisp-science)
- **License:** Apache-2.0
- **Homepage:** https://wispscience.com/

Install and usage instructions live in the source repository linked above.

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Versions

  • v0.1.0 Imported from the upstream source.