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SKILL verified Apache-2.0 Self-run

Bio Database Evidence

skill-foryourhealth111-pixel-vibe-skills-bio-database-evidence · by foryourhealth111-pixel

Unified biological database evidence owner. Use for gene annotation, variant clinical significance, cancer mutation evidence, GWAS trait associations, pathway mapping, target-disease evidence, protein structures, protein interaction networks, reference single-cell census queries, and cross-database biological ID mapping. Do not use for full single-cell analysis, bulk RNA-seq differential expressi…

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Install

$ agentstack add skill-foryourhealth111-pixel-vibe-skills-bio-database-evidence

✓ scanned · ✓ verified, works with Claude Code, Cursor, and more.

Security review

✓ Passed

No issues found. Passed automated security review. · v0.1.0 How review works →

  • Prompt-injection patterns
  • Secret / credential exfiltration
  • Dangerous shell & filesystem operations
  • Untrusted network calls
  • Known-malicious package signatures

What it can access

  • Network access No
  • Filesystem access No
  • Shell / process execution No
  • Environment & secrets No
  • Dynamic code execution No

From automated source analysis of v0.1.0. “Used” means the capability is present in the source — more access means more to trust, not that it’s unsafe.

View the full security report →

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Reliability & compatibility

Security review passed
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2mo ago

Declared compatibility

Claude CodeClaude Desktop

Compatibility is declared by the source manifest. End-to-end runtime verification is coming, see below.

Preview Execution monitoring

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About

Bio Database Evidence

Use This Skill For

Use this skill when the main task is biological database lookup, annotation, or evidence gathering across one or more biological sources:

  • Gene annotation, identifiers, RefSeq, Ensembl IDs, orthologs, VEP, GO, and genomic coordinates.
  • Variant clinical significance, VUS interpretation support, ClinVar review status, cancer mutations, and COSMIC evidence.
  • GWAS Catalog trait associations, rs IDs, p-values, summary statistics, and genetic epidemiology evidence.
  • Pathway mapping, ID conversion, KEGG pathways, Reactome enrichment, disease pathways, and pathway evidence.
  • Target-disease association evidence, tractability, safety, known drugs, and Open Targets evidence.
  • Protein structure evidence from AlphaFold DB or RCSB PDB, including UniProt IDs, mmCIF/PDB downloads, pLDDT, PAE, and structure metadata.
  • Protein-protein interaction evidence, STRING networks, hub proteins, and enrichment evidence.
  • Reference single-cell data lookup from CELLxGENE Census when the user asks for census metadata or expression data, not full downstream analysis.
  • Cross-database biological ID mapping and evidence tables across multiple resources.

Do Not Use This Skill For

  • Single-cell RNA-seq analysis, clustering, UMAP, marker genes, cell annotation, AnnData/h5ad container editing, or scVI/scANVI batch-correction planning. Use scanpy.
  • Bulk RNA-seq differential expression. Use pydeseq2.
  • BAM, SAM, CRAM, VCF, pileup, coverage, or region extraction as a primary file-processing task.
  • deepTools signal-track processing and heatmaps.
  • Protein language models, embeddings, inverse folding, or protein-design workflows.
  • Constraint-based metabolic modeling, FBA, or metabolic-engineering simulation.
  • BED/genomic interval embeddings, genomic-region ML, or gene regulatory network inference.
  • FCS or flow-cytometry file parsing.

Workflow

  1. Identify the biological entity type: gene, transcript, variant, pathway, target, protein structure, protein interaction, trait association, or reference cell population.
  2. Pick the narrowest source that answers the evidence question.
  3. Preserve source names, query terms, access dates, identifiers, and API caveats in the result.
  4. Return evidence in a table when comparing multiple sources.
  5. State when authentication, license, rate limits, or non-public access restricts a source.

Source Guide

See references/database-evidence-sources.md for source-specific boundaries and query notes.

Source & license

This open-source skill is cataloged on AgentStack and links to its original source — we do not rehost the code.

Install and usage instructions live in the source repository linked above.

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Versions

  • v0.1.0 Imported from the upstream source.